Type diabetes could farewell insulin

Type diabetes could farewell insulin
Lin Tang (Assumed name ) Have already said good-bye to the insulin treatment completely One year . This at a young age type diabetic is just 23 years old at the time of the onset, according to the inherent therapeutic idea, he lifetime this leave insulin treat . Fortunately, this guy becomes " L Eat crabs first " R Person. What Lin Tang chose is Shanghai Rui Jin hospital . At that time, doctor Gu WeiQiong of the division of endocrinology was looking for the case, the starting therapeutic new attempt of diabetes. This kind of treatment lets : Since the hematopoietic stem cell of peripheral blood of body transplants treating diabetes . Say, but move and plant with the patient's own stem cell a bit more popularly. It is still relatively narrow that suitable for treating crowds At the beginning of 2008, Rui Jin hospital just obtained permission of the relevant clinical new technology of Municipal Health Bureau. Some one day in March, Lin Tang appears in front of them. " It is narrower to suitable for becoming a crowd of patient of this kind of treatment. " Gu WeiQiong's detailed introduction screens some important principles of the patient's, including: Age is between the 14th years old to 30 years old, the time of onset is within 6 months. Type have diabetes hereditary background,it last diabetic by the 5%-10%s of the total number. Though like this, the researcher believes, the patient often receives a certain outside stimulus, for example the virus is infected, will bring out disease. Under such amazing function, the immune system of the human body has not worked, has produced a kind of antibody that can attack one's own Langerhans' islits cells, have caused blood glucose to rise. " The patient very painful, want, have several injection insulin every day, blood glucose can not be good in control all the same. " L Gu WeiQiong says, " R About 10 years after having illness coming on for patient of the big some type diabetes, will present complication. " Already inactive insulin of 4 patients Then, it is how to transplant to solve the problem? The doctor drew the hematopoiesis of peripheral blood and did cells through the patient's blood at first, and it is here to store - 80 In the environment of . The next step, to the chemotherapy which the patient inhibited to the immunity, that is to use medicines to come " L Attack " R That kind of antibody that will attack Langerhans' islits cells. After internal antibody in patient remove clean, go back, fail patient in the body hematopoietic stem cell and then. The whole treatment lasts 8 weeks . " We believe the stem cell is healthy, they will split up Langerhans' islits cells once again. " According to understanding, beginning of this research was 3 years ago. Doctor's treatment diabetic patients of 15 type in one U.S.A., the result has 13 patients to get rid of the insulin treatment, duration Damien 3. " Most medical personages have the wait-and-see attitude on this kind of therapeutic method. " L Gu WeiQiong seems very prudent, she says: " R We do not hope to advance rashly . " Division of endocrinology and hematology of Rui Jin hospital are jointly 10 patients have done the transfer operation. From looking at present, 4 people have already stopped using the Langerhans' islits plainly temporarily, 3 persons are in the course of decrement gradually, have 3 people are in planning to cure . Medical field, inside, though peripheral the intersection of blood and hematopoietic stem cell transplant person who treat diabetes still something new, but it is not strange to use this kind of method to treat one's own immune disease. In the world, diseases such as some rheumatoid arthritis, lupus erythematosus,etc., also been already using this kind of method. " Think we,type the diabeteses is too for immune diseases one's own,it so speak coherent theoretically. " Gu WeiQiong says. Still unknown question waits to analyse and explain However, the chemotherapy in the treatment may damage health cells, exert an influence on the liver, renal function. " This is a multiple-choice question put in front of patient, relative. " Gu WeiQiong has already met the family that nothing mind in the clinical practice, also met the family shrinking back. In addition, the international medical circle is in a kind of reason for looking around the state: This kind will be under the circumstances that virus,etc. should be surged too back to hematopoietic stem cell that fails, produce and kill the antibody which kills Langerhans' islits cells once again? Head of the department would rather only say the endocrine supersession of Rui Jin hospital : " This only we find at present every one may effecting a radical cure methods new of diabeteses, whether let us see that radically treat the dawn of disease, or need trying to find out further. " Gu WeiQiong says : " Looking at present, we still have a lot of things that can not provide the definite answer. We can only try to find out forward steadily, diligent with patient. " Chief correspondent Shi JiaQi of this newspaper
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