Specially change _'s general knowledge in sending lung fiber pathology

Specially change _'s general knowledge in sending lung fiber pathology
Specially sending lung fiber (idiopathic pulmonary fibrosis, IPF) Have acute, subnormal temperature and chronic difference according to the course of disease, the what is called Hamman-Rich syndrome genus is acute type, what clinic is seen more is the subnormal temperature and chronic type. European scholar call a disease more latent sources and cause fiber alveolus inflammation (cryptogenicfibrosingalveolitisCFA, CFA) . U.S.A. conventional IPF. The name of CFA prevails for a time in our country, recently but multi-purpose IPF. Disease this to send out, estimate morbidity 3- 5/10 Wan, account for all quality pulmonary tuberculosis 65% about. See that in every age group, and make diagnosis often among 50- 70 years old, the proportions 1.5- 2 of men and women: 1. The prognosis is bad, even early case reacts to hormone treatment, generally only there are 5 years in life cycle.
It is mainly alveolus inflammation that IPF early or acute issues of pathology change. It it is obvious on alveolus on wall and among lymphocyte, plasma cell, monocyte at quality, organize cell and a few grains of cells neutral acid not to be soaked. The alveolus needn't be involved, but there can be cells and the fibrin too to ooze out, include Model 2 alveolus cell and macrophage that is lossed. There can be albuminoid hyperplasia of network, but still little fibers in the interval of alveolus. As disease is developed, the inflammatory cell is oozed out and soaked and reduced gradually, become fibrous cell and collagenous thread hyperplasia, increase to be thick alveolus wall,type reduce alveolus cell,Model 2 alveolus cell hyperplasia, there are out of shape and not destroying in structure on alveolus, and can involve alveolus managing and thin bronchus. Appear person who fill the air later stage the intersection of lung and fiber take, angry Out of shape, expand into a bag, the size is from 1cm to count cm, " honeycomb lung " called . The intersection of disease and alveolus - the intersection of capillary and membrane this can have unsymmetry or lean towards the disposition to increase thick, the lung capillary bed is reduced. But there is not vascular inflammation of artery or swollen pathological change of the granulation on IPF pathology; Have their, quality pulmonary tuberculosis when should consider desmosis or other.
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