Specially sending _'s general knowledge of calm disease of hemosiderin

Specially sending _'s general knowledge of calm disease of hemosiderin
[Sum up ] Specially sending hemosiderin calm disease (idiopathic pulmomaryhae mosiderosis, IPH) A kind of cause of disease has not been bright, disease rarely that the intermittence bleeds in the lung. Report more than 200 in the world, report more than 120 (by 1994) at home . In the alveolus after the erythrocyte is destroyed, globin is absorbed, the hemosiderin causes reacting calmly in the lung tissue. Because bleed and can continue iron deficiency anemia of hair repeatedly. [Diagnose ] According to repeated hemoptysis, take the blood in the phlegm, the unclear spot shade of inner edge of lung, and continue iron deficiency anemia of the hair and make preliminary diagnosis, pass the phlegm liquid correctly, bronchus alveolus irritate lotion and lung live examine, finding including blue hemosiderin phagocyting, and getting rid of the intersection of heart and source Can be made a definite diagnosis of after the factor. [Treat the measure ] Can try out the hormone treatment, splash the Buddhist nun loose 1- 2mg/ (kg d) in acute one dailily ,2- The decrement after 3 weeks, the keeping amount arrives progressively. Deal with, include, to the iron pharmaceutical treatment which is short of iron anaemia, and continue and take place the antibiotic treatment after infecting to the ill. The course of disease differs greatly, report 68 examples, 20 (29%) die in 3 years ,Movable 17 (25%) ,Steady 12 (18%) ,Return to normal 19 (28%) . [The cause of disease is studied ] Not bright. Infer that relates to several respects, the abnormal development of leather cell at the lung, the quality among the lung exists the machinery of the capillary bleeds unstably and repeatedly; Immunological function obstacle, have in lungs such as 1/8 of the patients acidophil soaks, and loose cells, the plasma cell increases, some patients condense and collect and test the masculine gender. Some patients can erupt rheumatoid simultaneously, much arthritis, myocarditis, and Goodpasture syndrome appears. Other reasons mentioned are that animal's albumens are taken in, sucks noxious substance,etc. (such as organic pesticide) . [Pathology changes ] The lung weight increases, tangent plane it is obvious filling the air brown pigmentation, the mirror is examined there can be leather necrosis at alveoluses, unless hyperplasia, whose name is some expand capillary,alveolus and among last macrophages containing iron blood flavin at quality, there can be quality among filling the air nature fibers on later stage. The electric mirror has extensive capillary endothelial cell swelling to brief on, the inner membrane has albumens that is deposited. After the lung tissue is washed, dry, the iron content is still higher than normal lung by 5- 200 times while organizing. And proportional to condition. [Clinical manifestation ] This disease is seen more with the child, mainly regard 1- 7 years old as to see, 15% are over 15 years old, the ratio of the adult men and women is 2: 1,There is no obvious family. Symptom depends on the internal haemorrhage intensity of lung. Chronic continuously slightly to bleed there can be dry cough, weak, the skin is unconvincing, the weight is lightened and even the poke is pointed. Can take blood, spitting blood, low-heat in the phlegm at time when acute to bleed, the chest aches etc.. Can have difficulty in breathing on later stage, and even the manifestation not complete of heart function. And. The latent blood of stool is positive. The X-ray is shown as two lungs, unclear integration shade of spot of a plurality of edges of marching off into political wilderness, after the lung bleeds and stops, the shade absorbs taking a favorable turn during several weeks. Medium-sized persons who bleed of continuation, pathological change can take the form of corn of millet in the lung.
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